Cyclic Chiral Compounds

Celtic Catalysts has a range of highly functionalised cyclic chiral building blocks available. These biologically derived arene cis-dihydrodiols can be derivatised using robust, scaleable chemical methodologies to create a range of previously difficult to obtain compounds.

This range of compounds effectively constitutes a new chiral pool whose constituent compounds can be used in applications ranging from chiral reagents, chiral auxiliaries, chiral ligands and natural and unnatural product precursors.

These compounds are densely functionalised with numerous “tunable” functional handles thus rendering an effectively limitless number of derivative compounds available.

When it comes to handling and manipulating these compounds, Celtic Catalysts has an unrivalled experience and depth of knowledge. We have already made-to-order large number of derivatives (please see our representative derivatives list) and we are happy to take on any challenging synthetic target which could utilise these compounds.

The “take-home” message: If your target molecule contains a six-membered ring with multiple chiral centres – you should talk to Celtic Catalysts!

These compounds are ideal:
• as scaffolds for medicinal chemistry libraries
• for synthesis of:
- unusual coupling reagents e.g. chiral boronic acids
- pharmaceutically important templates (e.g. catechols, cyclic sulfates, boronic acids)

Please contact Celtic Catalysts regarding supply of these and related products.